作者Danielle (Pegg (on guard))
看板Biotech
标题Re: [求救] 想问免疫 抗原抗体反应的问题??
时间Wed Nov 7 16:34:25 2007
※ 引述《eriel (橘子数)》之铭言:
: 我觉得是不是要写出ELISA或是Flow cytometry之类的抗体抗原技术,然後讨论
: 之间的相同与相异处?
: 或者出题者目的其实是要考生了解抗体的一些特性:cross-reactivity or
: antibody affinity 跟 antibody avidity的不同?
: 这题目真的有点不太懂...
avidity: 指的是整个ab对整个抗原的结合能力
affinity: 指的是在一个antibody中 不同的complementory domain
对该epitope的结合力
找一段wikipedia的说明给你参考
In proteins,
avidity is a term use to describe the
combined strength of male
interactions. Avidity is distinct from
affinity, which is a term used to
describe the strength of a
single bond. As such, avidity is the combined
synergistic strength of bond affinities rather than the sum of bonds.
Avidity is commonly applied to antibody interaction. Where multiple, weak,
non-covalent bonds form between antigen and antibody. Individually, each bond
is quite readily broken, however when many are present at the same time the
overall effect results in synergistic, strong binding of antigen to antibody.
我不是很记得我有没有讲反 两年没念书了
有错还请板上各位先进帮忙修改
建议你去翻随便一本免疫学课本
都有很详细的说明
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※ 编辑: Danielle 来自: 140.109.55.225 (11/07 16:38)