Clinical correlation 1 Questions: 1.How and why, based on what serum biochemical exams, does Graves’disease diagnosed? 蔡承恩 2.Please point out the clinical signs the patient have and explain the physio-pathological mechanism 谢博尧 3.What is the mechanism by which high levels of iodine inhibit thyroid production? 吴铭展 4.How does propylthiouracil(PTU) inhibit thyroid synthesis? 王明方 5.What effect does pregnancy have on the free thyroid hormone level? 李柔慧 Clinical correlation 8 Questions 1.According to steroid hormone synthesis, what is the role/function of 11β -hydroxylase? Whatis the mechanisms and influences if the enzyme was deficient? 张维刚 2.Why the plasma ACTH and testosterone were increased in Anne’s case? 郭昭成 3.Why did Anne have increased size of clitoris and hyperpigmented genitalia? 刘臻 4.Did Anne have metabolic acidosis or alkalosis? Why? 林晋贤 5.How does the treatment: hydrocortisone and captopril work for Anne’s symptoms? 曾淑期 6.What would be happening in the process of development if Anne did not found to be 11β-hydroxylase deficient and had no treatments at all? 江品仪 ●书面收稿、PPT收稿：天使的右手 ●期末考命题：cfuryu ◎交稿时间：2010.6.2 晚上10点以前 {不准脱稿} ◎讨论时间：2010.6.9 下午3~5点 医学大楼601 THX --

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