作者libai8968 (vds)
看板ChemEng
标题[问题] 环的多寡和reactivity的关联
时间Thu Mar 4 17:26:56 2010
原题如下
a) Draw the structures of benzo[a]pyrene and of the two main products of
epoxidation, 4,5-benzo[a]pyrene oxide and 7,8-benzo[a]pyrene oxide.
b) Describe how 7,8-benzo[a]pyrene oxide is converted into the active
"diol epoxide" carcinogen. Discuss the possible reaction of this
"diol epoxide" with the amino group of 2'-deoxyguanosine.
c) What trend has been observed between the number of rings and the
reactivity of polynuclear aromatic hydrocarbons?
a,b 已解决
参考答案
http://herkules.oulu.fi/isbn9514270398/html/x203.html
想请教c该如何回答?
个人的想法是 越多环越容易稳定radical or carbocation
所以越多环 reactivity会越高
谢谢~
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