大家好 我们lab(隶属於MSKCC)最近在徵生物资讯人才 位於纽约上东区,周围环境算不错 若有兴趣者欢迎与我联络 谢谢大家。 Ray [email protected] ===== We are seeking a Computational Biologist to join the Lab and provide bioinformatics support in the development of next-generation sequencing applications to characterize the spectrum and clinical significance of genetic mutations in human tumors. Our lab uses mouse models, RNA interference (RNAi), and cancer genomics to identify components of tumor suppressor gene networks and understand the molecular determinants of treatment response. The goal is to identify genes required for tumor maintenance and to understand the mechanisms involved in tumor progression. These genes may be potential therapeutic targets to various cancer genotypes, such as lung, liver, colon, stomach, pancreatic, and prostate cancer. You Are - Experienced in the analysis of next-generation sequencing data - Ability to analyze and interpret single-cell RNA-seq data a plus. You Will: - Design, develop, and operate computational pipelines for the analysis of next-generation sequencing data. - Utilize gene set enrichment analysis to identify altered biological pathways that correlate with tumor progression. - Evaluate performance of novel technology platforms and assays. - Work directly with research groups to analyze biomedical data and address scientific problems with bioinformatics techniques and tools - Develop, refine, and improve bioinformatics tools for interpretation of large genomic data sets. - Manage and archive large data sets from next-generation sequencing experiments Does this sound like a match? If yes, you should apply. You Need - Experience with programming skill, such as R, Python, MatLab, etc. - Analysis of NGS data – RNA-seq and ChIP-seq - Variant calling – point mutations, indel, structural rearragenement, copy number changes - Build analysis pipeline, basic genomic sequencing alignment --

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