引用相关paper 的内容，大家自行参考，底下相关的参考文献我也附上去了，请各位详阅 (由於是版权物，我找了好久才找到人抓来给我，所以就不能直接分享，台大没有买此期刊 ) 另外~~我也开了关於食品安全资讯板面连署，请大家多多支持，为了你我健康，食品安 全多尽一分心力。 请大家到： LifeNewboard 帮我连署新板 这个是为了你我的知的资讯一起连署，也欢迎一同加入。 1 市民广场 报告站长 Ptt咬我 → 13 PttCosign 连署 ΣPtt连署群组 → 10 J_Cosign 连署 Σ生活娱乐馆 生活, 娱乐, 心情 → 1 LifeNewboard 申请 ◎生活娱乐群组连署板 若想加入连署请按 y 回应 申请新板 英文名称: foodsafe 中文名称: 食品安全资讯交流区 看板类别: 生活/美食/资讯 板主名单: kissinwang 申请原因: 从早期的千面人蛮牛事件，到现今的毒奶粉以及黄麴毒素相关食品 的影响，消费者对於目前的食品安全亮起了大大红灯，而政府推广 食品安全履历到基因改造食品等等，民众可以得到相关的资讯除了 官网(卫生署相关)之外，可以交流讨论的地方却没有，而PTT有着营 广大的群众，希望藉由这个板的成立让大家更容易了解食品安全资 连署结束时间: (1223493360)10/09/2008 03:16:00 Thu ----------支持---------- 1.kissinwang 食品安全资讯需要大家的支持。 来源:140.112.98.14 Melamine (1,3,5-triazine-2,4,6-triamine) is a nitrogen-based industrial chemical. It has been used in the manufacture of durable plastics such as table ware and cups. This use has led to a concern that melamine could migrate into food coming in contact with these plastics (1–4). Melamine can also be formed from the degradation of cyromazine, a larvacide used to prevent flies from hatching (5). High and continuous dietary exposure to melamine causes formation of bladder stones and increases incidence of urinary bladder tumors in male rats (6, 7). To date, no studies using human subjects have been reported. On March 15, 2007, a pet food manufacturer (Menu Foods, Ontario, Canada) alerted the U.S. Food and Drug Administration (FDA) to 14 animal deaths in the United States that appeared to be linked to pet food. In the following months, consumers and veterinarians reported more illnesses and deaths potentially associated with pet food. The FDA found melamine and melamine-related compounds such as cyanuric acid, ammeline, and ammelide in the pet food samples. Further investigation showed that some wheat gluten and rice protein imported from China as pet food ingredients were contaminated with melamine. Melamine and melamine-related compounds are not approved for use as an ingredient in pet food (8). Melamine in matrixes such as Chinese cabbage (9), soil (10), poultry meat(11), beverages (12), and catfish (13) has been determined by gas chromatography (GC), GC/mass spectrometry (GC/MS), high-performance liquid chromatography (HPLC) with UV detection, and LC tandem mass spectrometry (LC/MS/MS). Determination of melamine in pet food samples has been conducted by the FDA using an HPLC-UV procedure for quantitation and GC/MS for confirmation (14,15) However, currently there is no official method for melamine determination in pet food. This paper describes a new enzyme immunoassay (EIA) procedure and an HPLC-diode array detection (DAD) method that can be used to determine melamine in pet food. EIA is a good screening procedure because of its simplicity and low cost per analysis, and HPLC-DAD can be used for confirmation and quantification. Ultra-performance LC coupled with MS/MS (UPLC-MS/MS) was also tested for correlation with EIA and HPLC-DAD for melamine analysisof pet food. References (1) Bradley, E.L., Boughtflower, V., Smith, T. L., Speck, D.R., & Castle, L. (2005) Food Addit. Contam. 22, 597–606 (2) Kawai, S., Nagano, H., & Maji, T. (1989) J. Chromatogr. 477, 467–470 (3) Lund, K.H., & Petersen, J.H. (2006) Food Addit. Contam. 23, 948–955 (4) Martin, R.E., Hizo, C.B., Ong, A.M., Alba, O.M., & Ishiwata, H. (1992) J. Food Prot. 55, 632–635 (5) Cabras, P., Meloni, M., & Spanedda, L. (1990) J. Chromatogr. 505, 413–416 (6) OECD Screening Information DataSet (SIDS) Analysis: Melamine (June 2002) United Nations Environment Program, http://www.inchem.org/pages/sids.html (7) International Agency for Research on Cancer (1999) Vol. 73, IARC, Lyon, France (8) http://www.fda.gov/cvm/MenuFoodRecallFAQ.htm (9) Bardalaye, P.C., Wheeler, W.B., & Meister, C.W. (1987) J. Assoc. Off. Anal. Chem. 70, 455–457 (10) Yokley, R.A., Mayer, L.C., Rezaaiyan, R., Manuli, M.E., & Cheung, M.W. (2000) J. Agric. Food Chem. 48, 3352–3358 (11) Chou, S., Hwang, D., & Lee, H. (2003) J. Food Drug Anal. 11, 290–295 (12) Ishiwata, H., Inoue, T., Yamazaki, T., & Yoshihira, K. (1987) J. Assoc. Off. Anal. Chem. 70, 457–460 (13) Andersen, W.C., Turnipseed, S.B., Karbiwnyk, C.M., & Madson, M.R. (2007) U.S. FDA Laboratory Information Bulletin 23, No. 4396 (14) Updated FCC Developmental Melamine Quantitation (HPLC-UV) (April 2, 2007) http://www.fda.gov/cvm/melamine04022007.htm (15) GC/MS Screen for the Presence of Melamine, Ammeline, Ammelide and Cyanuric Acid (Version 2.1), http://www.fda.gov/cvm/GCMSMelamine.htm 引用内容： Kim, B., Perkins, L. B., Bushway, R. J., Nesbit, S., Fan, T., Sheridain, R., & Greene, V. (2008). Determination of melamine in pet food by enzyme immunoassay, high-performance liquid chromatography with diode array detection, and ultra-performance liquid chromatography with tandem mass spectrometry. Journal of Aoac International, 91(2), 408-413. -- http://kissinwang.ezyou.cc/ 化学/化学工程/生化科技BBS网路资源中心 http://groups.msn.com/chemicalBBScenter 欢迎将本板加入我的最爱：(C)lass【 分组讨论区 】→11国家研究院 政治, 文学, 学术 →1 Academy 研究 Σ科学学术研究院 → 2ˇBiology 生命 ●全国生物科技转信讨论区● --

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