[必]我已经读过置底版规、参考费率、发文必读公告，并愿意遵守规定：YES * 如已读过，请填 YES * 如未读过，请读过再重新发文。未填视为未读，一律删文处理并警告。 ────────────────────────────────────── [必]工 作 量： 12096 字（word） [必]工作报酬： 整份英润英 4500元 [必]涉及语言： 英文 [必]所属领域： 生物 医学 [必]文件类型： 提案 [必]截 稿 日： 20200715 [必]应徵期限： 徵到为止 [必]联络方式： 站内信 [必]付费方式： 承接工作後提供劳务报酬单，完稿後一周内由公司支付 ────────────────────────────────────── [选]工作要求： 文法纠正、语意正确即可。 [选]参考段落： [选]试 译 文： 请任选a或b段落润稿(站内信) a. It was previously shown, that exosomes secreted by cancer cells will sufficiently promote metastasis by various ways. For example exosomes derived from breast cancer and prostate cancer cells induce neoplasia through transfer of their miRNA cargo [14,15]. The plasticity of cancer cells may also be attributed in part to exosomes, with exosomal miR-200 from metastatic breast cancer cells enhancing the epithelial to mesenchymal transition (EMT) and metastasis of otherwise weakly metastatic breast cancer cells [16]. EVs participate in intercellular mitochondrial transfer. Horizontal transfer of mitochondria occurs through the transfer of either mitochondria-derived vesicles or intact mitochondria. To date, the mechanisms of intercellular transfer of free mtDNA across both mitochondrial inner and outer membranes and the plasma membrane remain elusive. b. Mitochondrial content, especially damaged or oxidized components resulting from IR exposure, can act as damage-associated molecular patterns (DAMPs) that activate an inflammatory response when present in the cytosol or released from cells [43]. The mitochondrial antiviral signaling protein (MAVS), located in the mitochondrial outer membrane, an innate immune signaling molecule, is involved in radiation response via its oligomerization mediated by radiation-induced ROS. MAVS is involved in IFN-β and IFN-stimulated gene expression in the response to IR. MAVS complexes promoting the nuclear translocation of the NF-κB and IRF3/7 transcription factors, respectively, and thus elicit the innate antiviral response. [选]其他事项：无 ────────────────────────────────────── --

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